Any person who is 18 years of age, or older, is eligible for the Moderna COVID-19 Vaccine (Bivalent). For the bivalent vaccine shot synthesised by Pfizer-BioNTech, any individual 12 years of age, or older, is eligible. However, the updated booster vaccine should only be administered if there is a gap of at least two months since the most recent vaccination round for each individual, according to the FDA.
In clinical trials, involving 1,400 participants, it was found that the bivalent vaccine enhances the immune response and provides a high level of protection against future infection and transmission. Per official estimates, over 200 million people will be eligible for the bivalent COVID-19 vaccine. There is no change in the dosage though.
Despite a fresh chemistry, the vaccine dosage and total antigen amount will remain the same. The monovalent Moderna vaccine — which earlier contained 50 micrograms of spike protein from the original SARS-CoV-2 virus — now contains 25 micrograms each of spike protein from the ancestral and the Omicron (BA.4 and BA.5) SARS-CoV-2 variant. In case of the Pfizer-BioNTech vaccine — which had a dosage amount of 30 micrograms — it’s bivalent version will now have 15 micrograms each of spike protein sourced from the original virus strain and the two Omicron variants.